By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX
نویسندگان
چکیده
منابع مشابه
By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX
The selection of nucleic acid aptamers is an increasingly important approach to generate specific ligands binding to virtually any molecule of choice. However, selection-inherent amplification procedures are prone to artificial by-product formation that prohibits the enrichment of target-recognizing aptamers. Little is known about the formation of such by-products when employing nucleic acid li...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0114693